Scientific publications

А.С. Горюнов, А.Г. Борисова.

Возможный механизм автоокисления гемоглобина в водных дисперсиях углеродных наноматериалов

// Труды КарНЦ РАН. No 5. Сер. Экспериментальная биология. 2014. C. 71-75

A.S. Goryunov, A.G. Borisova. Probable mechanism of haemoglobin autoxidation in water dispersions of carbon-based nanomaterials // Transactions of Karelian Research Centre of Russian Academy of Science. No 5. Experimental biology. 2014. Pp. 71-75

Keywords: haemoglobin, autoxidation, fullerene, shungite nanocarbon.

The effects of fulleren С₆₀ and shungite carbon water nanodispersions on human haemoglobin autooxidation in vitro have been examined. No effect of dispersion pH on the concentration-dependent ferrous heme oxidation in haemoglobin caused by fulleren С₆₀ and shungite nanocarbon has been revealed. Heme proteins autooxidation pathways consideration has shown that the most probable mechanism of С₆₀ 60 and shungite carbon effect on the haemoglobin autooxidation process is determined by their electron-acceptor capacity and involves a pH-independent transfer of an electron from a deoxyheme to an O₂ molecule, but not the dissociation of superoxide-anion.

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Last modified: November 18, 2014